Evidence for the use of haemofiltration in sepsis

Abstract 

Continuous renal replacement therapy has for some years been suggested as part of the first-line treatment of multiple organ dysfunction syndrome following severe sepsis and related insults. We describe how this therapy works and discuss the evidence that exists for its use. Although most of the evidence of benefit to patients is anecdotal, sufficient has been published to suggest that these treatments may be beneficial and warrant further study in this area.

Keywords: haemofiltration, sepsis, multiple organ failure, renal replacement therapy

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• f1 Correspondence to: CB. Tel./Fax: +44 (0) 141-201 0186; E-mail: crispin.best@yorkhill.scot.nhs.uk