Current Paediatrics
Volume 16, Issue 6 , Pages 447-452, November 2006

Applied physiology: Immune competence

Department of Paediatric Immunology, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK

Summary 

The immune system has evolved in order to prevent invasion by foreign organisms. This review outlines the principles and mechanisms of innate and acquired immunity, explaining each aspect of the response and how innate and acquired systems interact. The effects of deficiency in particular components are illustrated with reference to specific immunodeficiencies.

Keywords: Innate immunity, Acquired immunity, Antibody diversity, Immunodeficiency

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PII: S0957-5839(06)00103-5

doi:10.1016/j.cupe.2006.07.012

Current Paediatrics
Volume 16, Issue 6 , Pages 447-452, November 2006

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