Epilepsy is a major cause of morbidity in autism. The diagnosis and management of epilepsy in autism is complicated by a high prevalence of co-morbid neurodevelopmental disorders and co-medication. The prevalence of epilepsy is highest in those autistic children with cognitive, motor and receptive language difficulties. The underlying pathophysiology of Autism, its high rate of paroxysmal electroencephalographic abnormalities and its association with epilepsy is debated. Suggestions regarding the appropriate investigation and management of autistic children presenting with possible epilepsy are outlined.
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